Evolution Suisse 2026

Data#

What exists#

Dataset Format Status
SDS-PAGE and clear-native gel images TIFF / PNG from gel imager Collected across May–September
Anti-His immunoblots TIFF / PNG Collected
SEC chromatograms UNICORN export Collected, multiple runs per construct
DLS distributions Instrument export Collected
A280 step-by-step purification tables Spreadsheet Collected
Sanger and whole-plasmid sequencing AB1 / FASTA, aligned in Benchling Collected
Growth curves Not yet — awaits the selection screen
Selection screen dose–response Not yet
Evolution campaign sequencing Not yet

Purification step accounting#

The most useful thing produced this season is not a single measurement but the per-step aliquot series: an aliquot retained at every stage of every purification, with A280 and a gel lane for each. That is what turns "the protein disappeared" into "the protein is in the pellet after lysis", which is a debuggable statement.

Sequencing#

All constructs were verified by Sanger sequencing of assembly junctions and, where it mattered, by whole-plasmid sequencing. Alignments are maintained in Benchling.

Negative sequencing results are retained deliberately — the clones that came back as empty backbone or as an unrelated insert are part of the record of how long the assemblies took to get right.

Availability#

Raw data will be deposited alongside the report. Sequences of all constructs will be provided as supplementary information; plasmid maps are maintained in Benchling.

Not yet populated

This page lists what has been collected, not links to it. Deposition happens with the report submission.