Semi-rational directed evolution of a Deepsea-derived P450S18 for Phenazines Construction

Functional Chemical Experiment Documentation

左侧默认图 左侧悬停图

Team Members

Member 1

Wenli Li

Supervisor

  Wenli Li obtained her Ph.D. in microbial genetics in 2003 at the Institute of Microbiology, Chinese Academy of Sciences. From 2004 - 2008, she carried out postdoctoral research in School of Pharmacy, University of Wisconsin - Madison, USA. After a research career in the PPD company in the States (2008 - 2009), she was appointed as a Full Professor in the School of Medicine and Pharmacy, Ocean University of China. Her current research focuses on the synthetic biology of secondary metabolites from marine microorganisms, and lead compounds discovery by genome mining and combinatorial strategies. She has published over 80 scientific papers on these and related topics.

Member 2

Fei Xiao

Mentor

  Fei xiao received her B.s. degree in Pharmacy from Ocean University of china (Qingdao China) in 2013 and her Ph.D degree in Biochemistry with Prof. Wenli li from Ocean University of China in 2019. She is currently an associate professor in Ocean University of China,School of Pharmacy and Medicine. She focuses on the naturalproducts biosynthesis and engineering, and the study of biosynthetic enzyme mechanisms.

Member 3

Mengqi Zhao

Team Leader

  Key Laboratory of Marine Drugs, Ministry of Education of China, school of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

Member 4

Qingrui Liu

Student

  Key Laboratory of Marine Drugs, Ministry of Education of China, school of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

Member 5

Xinming Hu

Student

  Key Laboratory of Marine Drugs, Ministry of Education of China, school of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

Member 6

Yuting Wu

Student

  Key Laboratory of Marine Drugs, Ministry of Education of China, school of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

Member 7

Duo Fu

Student

  Key Laboratory of Marine Drugs, Ministry of Education of China, school of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.