Evolution’s Past and Present
—— From Nature to the Laboratory
Directed evolution, a laboratory simulation of Darwinian natural selection, employs random mutagenesis and recombination coupled with human-designed selection pressures to sift through proteins for those exhibiting desired characteristics, thereby facilitating the artificial evolution of molecules and cells.
The Shape-Shifting Weapon
—— Adaptive IL-2R Agonist Expands Effector Cells While Evading Suppression
Drawing inspiration from Sun Wukong’s golden cudgel, famed for its dynamic expansion and contraction, this study designs a pH-responsive IL-2R agonist that adapts within tumors to selectively empower NK/T cells against cancer.
Contact us
Email: Synthlmmunol_NMU@163.com
Address: National Key Laboratory of lmmunity & Inflammation, Institute of lmmunology, Naval Medical University, Shanghai 200433.China
This project is supported by DAKEWE
