| Date | Member | Experiment | Result |
|---|---|---|---|
| 2023/9/1 | K.L.Y. | NK-92, BBζ cells and BBζ-M NK cells(1×107/mouse) were injected in mice via tail vein. | The efficacy of the cells was detected. |
| 2023/9/4 | Q.X.R. | After 72 hours, the persistence of NK cells in tumor tissues was collected and determined by immunofluorescence (IF) | Tumor tissue sample were obtained. |
| 2023/9/4 | Q.X.R. K.L.Y. | Tumor tissues were formalin-fixed and paraffin-embedded. Incubated with fluorescence-conjugated antibody targeting CD56 (NCAM1 (CD56) (E7X9M) Rabbit mAb, CST, 99746). Then, incubated with fluorescence conjugated antibodies. Images were captured with a 63×/1.4-NA oil-immersion objective. Leica confocal software (Leica, Germany) was used to process images. | IF were performed. |
| 2023/8/1 | K.L.Y. Z.S.L. | 5×106 Hep3B cells in 50 μL of HBSS were injected via subcutaneous injection into the right flank of NCG mice. | Hep3B hepatocellular subcutaneous tumor model was constructed. |
| 2023/8/10 | K.L.Y. | NK-92, BBζ cells and BBζ-M NK cells(1×107/mouse) were injected in mice via tail vein 3 times. | The efficacy of the cells was detected. |
| 2023/8/31 | Q.X.R. | After 3 times of treatment, tumor tissues were obtained | Tumor tissue sample were obtained. |
| 2023/8/3 | K.L.Y. Z.S.L. | 5×106 TE1cells in 50 μL of HBSS were injected via subcutaneous injection into the right flank of NCG mice. | TE1 esophageal cancer cell subcutaneous tumor model was constructed. |
| 2023/8/10 | Y.X.L. | NK-92, BBζ cells and BBζ-M NK cells(1×107/mouse) were injected in mice via tail vein. | The efficacy of the cells was detected. |
| 2023/8/31 | Q.X.R. | After 3 times treatment, the tumor tissues were obtained. | Tumor tissue samples were obtained. |
| 2023/9/1 | K.L.Y. Z.S.L. | 5×106 SNU478cells in 50 μL of HBSS were injected via subcutaneous injection into the right flank of NCG mice. | SNU478 gastrointestinal subcutaneous tumor model was constructed. |
| 2023/9/10 | Y.X.L. | NK-92, BBζ cells and BBζ-M NK cells(1×107/mouse) were injected in mice via tail vein. | The efficacy of the cells was detected. |
| 2023/10/1 | Q.X.R. | After 3 times treatment, the tumor tissues were obtained. | Tumor tissue samples were obtained. |